{"id":76176,"date":"2017-02-20T08:48:25","date_gmt":"2017-02-20T13:48:25","guid":{"rendered":"https:\/\/www.ucf.edu\/news\/?p=76176"},"modified":"2018-07-02T14:19:31","modified_gmt":"2018-07-02T18:19:31","slug":"light-beam-replaces-blood-test-heart-surgery","status":"publish","type":"post","link":"https:\/\/www.ucf.edu\/news\/light-beam-replaces-blood-test-heart-surgery\/","title":{"rendered":"Light Beam Replaces Blood Test During Heart Surgery"},"content":{"rendered":"<p>A 麻豆原创 professor has invented a way to use light to continuously monitor a surgical patient\u2019s blood, for the first time providing a real-time status during life-and-death operations.<\/p>\n<p>The technology developed by 麻豆原创 scientist Aristide Dogariu uses an optical fiber to beam light through a patient\u2019s blood and interpret the signals that bounce back. Researchers believe that in some situations it could replace the need for doctors to wait while blood is drawn from a patient and tested.<\/p>\n<p>\u201cI absolutely see the technique having potential in the intensive care setting, where it can be part of saving the lives of critically ill patients with all kinds of other disorders,\u201d said Dr. William DeCampli, who is chief of pediatric cardiac surgery at Arnold Palmer Hospital for Children and a professor at the 麻豆原创 College of Medicine. DeCampli helped develop the technology and test it during surgery on infants.<\/p>\n<p>During surgery, physicians are wary of the patient\u2019s blood coagulating, or clotting, too quickly. A clot can lead to life-threatening conditions such as stroke or pulmonary embolism. Coagulation is of particular concern during cardiovascular surgery, when a clot can shut down the heart-lung machine used to circulate the patient\u2019s blood.<\/p>\n<p>Doctors administer blood-thinning medication to prevent coagulation. But every 20-30 minutes, blood must be withdrawn and taken to a lab for a test that can take up to 10 minutes. That\u2019s a slow process with gaps of time without up-to-date information, especially in operations that can last four hours or more.<\/p>\n<p>Dogariu, a Pegasus Professor in 麻豆原创\u2019s College of Optics &amp; Photonics, developed a machine with an optical fiber that can tap directly into the tubes of the heart-lung machine. The optical fiber beams light at the blood passing through the tube and detects the light as it bounces back.<\/p>\n<p>As reported in a <a href=\"https:\/\/www.nature.com\/articles\/s41551-017-0028\">paper published recently in the journal <em>Nature Biomedical Engineering<\/em><\/a>, the machine constantly interprets the light\u2019s back-scatter to determine how rapidly red blood cells are vibrating. Slow vibration is a sign blood is coagulating and a blood-thinner may be needed.<\/p>\n<p>The technology can alert doctors at the first sign of clotting, and provide nonstop information throughout a long procedure.<\/p>\n<p>\u201cIt provides continuous feedback for the surgeon to make a decision on medication,\u201d Dogariu said. \u201cThat is what\u2019s new. Continuous, real-time monitoring is not available today. That is what our machine does, and in surgeries that can last for hours, this information can be critical.\u201d<\/p>\n<p>Doctoral student Jose Rafael Guzman-Sepulveda, who has studied real-time blood monitoring during surgery for the last year, helped to design the instrumentation and integrated it into the heart-lung machine.<\/p>\n<p>\u201cI needed to master not just the optical and signal processing instrumentation, but also the technology of the heart-lung machine, which I was able to do,\u201d he said.<\/p>\n<p>Over the past year, DeCampli tested the technology during cardiac surgeries on 10 infants at Arnold Palmer Hospital for Children, which consistently ranks among the best centers in the nation for pediatric cardiac surgery and is the leading center in Orlando.<\/p>\n<p>The successful tests were the end result of a relationship facilitated by 麻豆原创, DeCampli said. DeCampli, who has also been a professor of surgery at the 麻豆原创 College of Medicine since its inception 10 years ago, noted that the university encourages interdisciplinary collaboration among its faculty as a way to spark innovative breakthroughs. That\u2019s how he came to work with Dogariu, who has spent years researching the application of light-detection technology in industrial uses like the manufacture of semiconductors and paints.<\/p>\n<p>\u201cThese things come about because of collaboration between a top-ranked engineering university and a top-ranked children\u2019s hospital all in one city,\u201d DeCampli said. \u201cI think it\u2019s the perfect way to make advances in medicine that are at the engineering frontiers.\u201d<\/p>\n<p>Their recently published paper is based on a small, proof-of-concept study. A larger study is in the works.<\/p>\n","protected":false},"excerpt":{"rendered":"A 麻豆原创 professor has invented a way to use light to continuously monitor a surgical patient\u2019s blood, for the first time providing a real-time status during life-and-death operations. The technology developed by 麻豆原创 scientist Aristide Dogariu uses an optical fiber to beam light through a patient\u2019s blood and interpret the signals that bounce back. Researchers believe that&hellip;","protected":false},"author":30,"featured_media":76177,"comment_status":"open","ping_status":"closed","sticky":false,"template":"template-twocol.php","format":"standard","meta":{"_acf_changed":false,"lazy_load_responsive_images_disabled":false,"footnotes":"","_links_to":"","_links_to_target":"","_wp_rev_ctl_limit":""},"categories":[5,12,23,24],"tags":[6395,979,981,15761,14916],"tu_author":[],"class_list":["post-76176","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-colleges","category-health","category-research","category-science-technology","tag-aristide-dogariu","tag-college-of-medicine","tag-college-of-optics-and-photonics","tag-pegasus-briefs","tag-research"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Light Beam Replaces Blood Test During Heart Surgery<\/title>\n<meta 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